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Woofun AI reports that cryptocurrency-related equities experienced significant pre-market gains on August 21. MicroStrategy (MSTR) led the sector with an 11.12% increase, followed by Coinbase (COIN) up 6.75% and Circle (CRCL) rising 6.42%. Other notable movers included SBET at 4.45%, BMNR at 4.96%, Robinhood (HOOD) at 4.68%, and PURR at 3.87%.